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Comments on: The Semaglutide (Wegovy) Clinical Trial: Or How headline numbers mess with both Doctors and Patients minds https://garycornell.com/2024/01/09/the-semaglutide-wegovy-clinical-trial-or-how-headline-numbers-mess-with-both-doctors-and-patients-minds/ - with an occasional random thought on random topics. All material is owned and copyrighted © by Gary Cornell but may be freely quoted Sat, 13 Jan 2024 19:24:27 +0000 hourly 1 https://wordpress.org/?v=6.5.3 By: admn https://garycornell.com/2024/01/09/the-semaglutide-wegovy-clinical-trial-or-how-headline-numbers-mess-with-both-doctors-and-patients-minds/#comment-639 Sat, 13 Jan 2024 19:24:27 +0000 https://garycornell.com/?p=709#comment-639 In reply to Benji Mathew.

Yes the absolute risk reduction would “only” be 8% but it doesn’t change the fact that ARR is a better measure than RRR. RRR which tells you nothing without knowing how prevalent the disease is in the untreated group – in which case you can recover ARR from the combination of prevalence and RRR. After all, if you have an extremely rare disease, knowing you have a 99%, RRR still doesn’t tell you what you want to know.

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By: Benji Mathew https://garycornell.com/2024/01/09/the-semaglutide-wegovy-clinical-trial-or-how-headline-numbers-mess-with-both-doctors-and-patients-minds/#comment-638 Sat, 13 Jan 2024 19:00:57 +0000 https://garycornell.com/?p=709#comment-638 Your framing of relative risk is unfair. If heart disease was completely cured in the semaglutide group and cardiovascular events went to zero that would obviously be game-changer. But the absolute risk reduction would only be 8%. Relative risk is more relevant and so it’s justifiably highlighted more.

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By: The economics of semaglutide - Marginal REVOLUTION https://garycornell.com/2024/01/09/the-semaglutide-wegovy-clinical-trial-or-how-headline-numbers-mess-with-both-doctors-and-patients-minds/#comment-634 Sat, 13 Jan 2024 10:47:10 +0000 https://garycornell.com/?p=709#comment-634 […] is more from Gary Cornell, mostly about the degree of […]

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